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Cancer Clinical Trials

Site: Hematologic/Blood-Related

The most recent listing of current clinical trials for hematologic and blood-related cancers — including blood and marrow transplant/BMT, leukemia, non-Hodgkins lymphoma, Hodgkin's disease/lymphoma and multiple myeloma — appears below. Should you be interested in learning more about any of these clinical trials, please use our Contact Us form.
 

Site: Hematologic/Blood-Related
(Includes Blood and Marrow Transplant/BMT,
Leukemia, Non-Hodgkins Lymphoma,
Hodgkin's Disease/Lymphoma,
Lymphoma and Multiple Myeloma)

Protocol ID    Title

In-House-GVHD    Assessment of Regulatory T Cells Prior to and Following Autologous Stem Cell Transplant for Multiple Myeloma

Keywords: Autologous Stem Cell Transplant for Multiple Myeloma

RDCRN 6501    Longitudinal Study of Immune Mediated Disorders after Allogeneic Hemotopoietic Cell Transplantation

Keywords: Allogeneic Hemotopoietic Cell Transplantation

In-House-GVHD    Acquisitions of Graft v. Host Disease Sample in Pre-Clinical Studies

Keywords: Graft v. Host Disease

Industry    A Multicenter Phase I Clinical and Pharmacokinetic study of DCC-2036 in Subjects with Philadelphia Chromosome Positive Leukemias

Keywords: Philadelphia Chromosome Positive Leukemias

C10403    An Intergroup Phase II Clinical Trial of Adolecents and Young Adults with Untreated Acute Lymphoblastic Leukemia

Keywords: Adolecents and Young Adults with Untreated Acute Lymphoblastic Leukemia

In-House    Laboratory Studies of Iron Metabolism in Blood Cells from Patients with Hematochromatosis

Keywords: patients with hematochromatosis

In-House: Pre-Clinical
Vaccine for MM
   Pre-Clinical Studies on Vaccine Derived From Patient-Derived Myeloma Cells

Keywords: Multiple Myeloma

FH 2184.00    Chronic GVHD Protocol: Improving Outcomes Assessment in Chronic GVHD

Keywords: Chronic GVHD

In-House: Haplo-Cord    Phase II Study: Myeloablative Human Stem Cell Transplant (HSCT) Using Selected Mismatched Related Donor and One Umbilical Cord Unit

Keywords: Human Stem Cell Transplant

E2903    Phase II Trial of Pentostatin, Cyclophosphamide and Rituximab (PCR) Followed by Campath-1H for Previously Treated Relapsed or Refractory Patients with Chronic Lymphocytic Leukemia

Keywords: Previously Treated Relapsed or Refractory Patients with Chronic Lymphocytic Leukemia

KP- 339    A Phase III Randomized Study to Assess the Efficacy and Safety or Perifosine Added to the Combination of Bortezomib and Dexamethasone in Multiple Myeloma Patients Previously Treated with Bortezomib

Keywords: Multiple Myeloma Patients Previously Treated with Bortezomib

CTN 0701    PhaseII Trial of Non-Myeloablative Allogeneic Hematopoietic Cell Transplantation for Patients with Relapsed Follicular Non-Hodgkin's Lymphoma Beyond First Complete Response

Keywords: Patients with Relapsed Follicular Non-Hodgkin's Lymphoma Beyond First Complete Response

CTN 0802    A Multi-Center Randomized, Double Blind, Phase III Trial Evaluating Corticosteroids with Mycophenolate Mofetil vs. Corticosteriods with Placebo as Initial Systemic Treatment of Acute GVHD

Keywords: Treatment of Acute GVHD

E1906    A Phase II Randomized Trial of Carboplatin and Topotecan; Flavopiridol, Mitoxantrone and Cytosine Arabinoside; and Sirolimus, Mitoxantrone, Etoposide and Cytosine Arabinoside for the Treatment of Adults with Primary Refractory or Initial Relapse of Acute Myelogenous Leukemia

Keywords: Adults with Primary Refractory or Initial Relapse of Acute Myelogenous Leukemia

E2905    Randomized Phase III Trial Comparing the Frequency of Major Erythroid Response (MER) to Treatment with Lenalidomide (Revlimid ®) Alone in Combination with Epoetin Alfa (Procrit ®) in Subjects with Low- or Intermediate -1 Risk MDS and Symptomatic Anemia

Keywords: Low- or Intermediate -1 Risk MDS and Symptomatic Anemia

FH 2241.00    Sequential Autologous HCT/ Nonmyeloablative Allogenic HCT using Related, HLA-Haploidentical Donors for Patients with High-Risk Lymphoma, Multiple Myeloma, or Chronic Lymphocytic Leukemia

Keywords: Patients with High-Risk Lymphoma, Multiple Myeloma, or Chronic Lymphocytic Leukemia

C-AML    Randomized Phase III Study of Elacytarabine vs. Investigators Choice in Patients with Late Stage Acute Myeloid Leukemia

Keywords: Late Stage Acute Myeloid Leukemia

AT7519M/0004    A Phase I/II Open-Label Multicenter Study of AT7519M Alone and in Combination with Bortezomib in Patients with Previously Treated Multiple Myeloma

Keywords: Patients with Previously Treated Multiple Myeloma

CTN 0702    A Trial of Single Autologous Transplant with or without Consolidation Therapy vs. Tandem Autologous Transplant with Lenalidomide Maintenance for Patients with Multiple Myeloma

Keywords: Patients with Multiple Myeloma

PX-171-009    A Randomized, Multicenter, Phase III Study Comparing Carfilzomib, Lenalidomide, and Dexamethasone (CRd) vs Lenalidomide and Dexamethasone (Rd) in Subjects with Relapsed Multiple Myeloma

Keywords: Patients with Relapsed Multiple Myeloma

WON HO10407    A Phase II Study of Bortezomib and Temsirolimus for Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma

Keywords: Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma

CIBMTR RDSafe    A Multicenter Study of Hematopoietic Stem Cell Donor Safety and Quality of Life

Keywords: Hematopoietic Stem Cell Donor Safety and Quality of Life

StemEx    A Multi-Center, Multi-National, Historical Cohort Controlled Study to Evaluate Efficacy and Safety of Transplantation of StemEx, Umbilical Cord Stem and Progenitor Cells Expanded Ex-Vivo, in Subjects with Hematological Malignancies following Myeloablative Therapy

Keywords: Hematological Malignancies

CTN 0901    A Randomized, Multi-Center, Phase III Study of Allogeneic Stem Cell Transplantation Comparing Regimen Intesnsity in Patients with Myelodysplastic Syndrome or Acute Myeloid Leukemia

Keywords: Myelodysplastic Syndrome or Acute Myeloid Leukemia

E2906    Phase III Randomized Trial of Clofarabine as Induction and Post-Remission Therapy vs. Standard Daunorubicin & Cytarabine Induction and Intermediate Dose Cytarabine Post-Remission Therapy, Followed by Decitabine Maintenance vs. Observation in Newly Diagnosed Acute Myeloid Leukemia in Older Adults (Age >60 Years)

Keywords: Newly Diagnosed Acute Myeloid Leukemia in Older Adults (Age >60 Years)

C05013    An Open-Label, Randomized, Phase II Study to Assess the Effectiveness of RCHOP with or without VELCADE in Previously Untreated Patients with Non-Germinal Center B-Cell-like Diffuse Large B-Cell Lymphoma

Keywords: Diffuse Large B-Cell Lymphoma

FH- 2431.00    Long-Term Outcomes of Participants in Clinical Studies of Immune-Mediated Disorder

Keywords: Immune-Mediated Disorder

In-house    Phase I-II Study Using Tocilizumab for Treatment of Steroid Refractory Acute Graft Versus Host Disease

Keywords: Refractory Acute Graft Versus Host Disease

E2408    A 3 Arm Randomized Phase II Trial of Bendamustine-Rituximab (BR) Followed by Rituximab vs. Bortezomib-BR (BVR) Followed by Rituximab vs. BR Followed by Lenalidomide/ Rituximab in High Risk Follicular Lymphoma

Keywords: High Risk Follicular Lymphoma

Industry-Multiple Myeloma    Phase I/II, Open-Label, Multicenter Study of ACY-1215 Administered Orally as Monotherapy and in Combination with Bortezomib and Dexamethasone for the Treatment of Relapsed or Relapsed/ Refractory Multiple Myeloma

Keywords: Relapsed or Relapsed/ Refractory Multiple Myeloma

C16005    An Open-Label, Dose-Escalation Phase I/II Study of the Oral Form of MLN9708 a Second Generation Proteasome Inhibitor, Administered in Combination with Lenalidomide and Low-Dose Dexamethasone in Patients with Newly Diagnosed Multiple Myeloma Requiring Systemic Treatment

Keywords: Newly Diagnosed Multiple Myeloma

FH-2230.00    A Phase I/II Study Evaluating the Safety and Efficacy of Adding a Single Prophylactic Donor Lymphocyte Infusion (DLI) of Natural Killer Cells Early After Nonmyeloablative, HLA Haploidentical Hematopoietic Cell Transplantation

Keywords: Nonmyeloablative, HLA Haploidentical Hematopoietic Cell Transplantation

FH-2448.00    A Randomized Phase II Study to Determine the Most Promising Postgrafting Immunosuppression for Prevention of Acute GVHD after Unrelated Donor Hematopoietic Cell Transplantation using Nonmyeloablative Conditioning for Patients with Hematologic Malignancies: A Multicenter Trial

Keywords: Donor Hematopoietic Cell Transplantation

 

 

Last Review Date: Jan. 31, 2012

Online Editor(s): Richard Petre

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